Pharmaceutical Chemistry-Iia (Biochemistry)

Role of Pharmaceutical Biochemistry in the health profession. Nature of biochemical reactions.

1. Carbohydrates: Chemistry, Classification, Reactions of Carbohydrates, Optical activity, Biological and pharmaceutical importance of carbohydrates.
2. Lipids: Chemistry of Fatty acids and Lipids, Classification (Saponifiable and non-saponifiable lipids, Simple, Complex and Derived lipids), Reactions of Fatty acids and other Lipids, Essential fatty acids, Biological and pharmaceutical importance of lipids.
3. Proteins and Amino acids: Chemistry, Classification of proteins and amino acids, Reactions of proteins and amino acids, Organizational levels, Macromolecular nature of proteins, Biological and pharmaceutical importance of proteins and amino acids.
4. Nucleic Acids: Chemistry, Types (DNA, RNA, mRNA, tRNA, rRNA), Purine and Pyrimidine bases, Nucelosides, Nucelotides, Structures of nucleic acids, Biological and pharmaceutical importance of nucleic acids.
5. Vitamins: Chemistry, Classification (Fat-soluble and water-soluble vitamins), Biological and pharmaceutical importance of vitamins.
6. Hormones: Chemistry, Classification (Proteinous and non­proteinous hormones, amino acid derivatives, steroids), Biological and pharmaceutical importance of hormones.
7. Enzymes: Chemistry, Classification, Mode of action, Kinetics (Michaelis Menten Equation and some modifications), Inhibition, Activation, Specificity, Allosteric enzymes, Factors affecting the rate of an enzyme-catalyzed reaction, Biological and pharmaceutical importance, Mechanism of action of some important enzymes (Chymotrypsin, Ribonuclease).