The topics will be taught with special reference to their Pharmaceutical Applications.
Chemical Bonding and concept of Hybridization, Conjugation, Resonance (Mesomerism), Hyperconjugation, Aromaticity, Inductive effect, Electromeric effect, Hydrogen bonding, Steric effect, Effect of structure on reactivity of compounds, Tautornerism of Carbonyl Compounds, Nomenclature of Organic Compounds.
Stereochemistry/ Conformational Analysi
Stereoisomerism, optical isomerism; Molecules with more than one chiral center, Geometrical isomerism, Resolution of racemic mixture, Conformational analysis.
General Methods Of Preparation, Properties, Identification Test And Pharmaceutical Applications Of The Following Classes And Their Analogues:
- Alkane, Alkenes, Alkynes, Aromatic compounds
- Alkyl halide, Alcohol, phenols, ethers, amines
- Ketones, Aldehydes
- Acids, Esters, Amides and derivatives
Nucleophilic, Electrophilic Substitution Reaction In Aliphatic And Aromatic Systems:
Orientation In Electrophilic Substitution Reactions On Benzene Ring:
Practicals of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Organic analysis: Identification of unknown simple organic compounds.