Introduction to Sterilization/ Disinfection. Fermentation.Pharmaceutical products produced by fermentation process (Penicillins, Cepalosporins, Gentamycin, Erythromycin, Tetracyclines, Rifamycin, Griseofulvin).
Introduction and types of Immunity: Specific and non-specific (Cellular basis of Immune response. Immunity, autoimmunity, tolerance. Antigen. Anti-bodies). Antigen-Antibody reactions and their clinical and diagnostic applications. Hypersensitivity and allergy. Drug allergy mechanism. Vaccination: Introduction and aims. Types of Vaccines. Current vaccine practices.
Factory & Hospital Hygiene Including Good Manufacturing Practices
Introduction, Control of Microbial contamination during manufacture. Mnaufacture of Sterile products, A Guide to Current Good Pharmaceutical Manufacturing Practices.
Introduction To Diseases
Dengue fever, Bird flu, SARS, or other prevailing diseases of bacteria and virus.
Practical of the subject shall be designed from time to time on the basis of the above mentioned theoretical topics and availability of the facilities, e.g. Sterilization of Glassware and pharmaceutical products by various methods. Microbiological assays of: Anti-biotics and vitamins. Preparation of general and selective Media and culturing of microorganisms. Total and viable counts of micro-organism. Morphological and selective biochemical characterization of some specimen. Staining of Bacteria: Gram method, Acid fast, Giemasas staining, Capsule staining, Flagella staining and Spore staining. Microbiological analysis of air, water and soil (Note: A minimum of 10 practicals will be conducted).