Students will acquire knowledge and understanding about aromatic substitution reactions and oxidation and reduction as well as pericyclic reactions.
Aromatic Substitution Reactions:
Mechanisms of aromatic reactions including electrophilic and nucleophilic substitutions, effect of substituents on orientation and reactivity.
Common oxidizing and reducing reagents, reactions involving elimination of H, cleavage of C-C bond, replacement of hydrogen by oxygen, and addition of oxygen to substrates, reaction involving replacement of oxygen by hydrogen, removal of oxygen from the substrates and reduction with cleavage.
Introduction to pericyclic reactions, frontier orbital theory, mechanisms of electrocyclic, cycloaddition and sigmatropic reactions.
Experiments involving aromatic substitution, oxidation/reduction reactions and pericyclic reactions, nitration of nitrobenzene to meta-dinitrobenzene, reduction of meta- dinitrobenzene to meta-nitroaniline, sulphonation of aniline, oxidation of benzaldehyde, oxidation of cyclohexanol to cyclohexanone. Preparation of benzoic acid and benzyl alcohol from benzaldehyde using Cannizzaro’s reaction.