Course Objectives:

Students   will   acquire   knowledge   and   understanding   about   aromatic substitution reactions and oxidation and reduction as well as pericyclic reactions.

Course Contents:


Aromatic Substitution Reactions:

Mechanisms of aromatic reactions including electrophilic and nucleophilic substitutions, effect of substituents on orientation and reactivity.

Oxidation-reductions Reactions:

Common oxidizing and reducing reagents, reactions involving elimination of H, cleavage of C-C bond, replacement of hydrogen by oxygen, and addition of oxygen to substrates, reaction involving replacement of oxygen by hydrogen, removal of oxygen from the substrates and reduction with cleavage.
Pericyclic Reactions:
Introduction  to  pericyclic  reactions,  frontier  orbital  theory,  mechanisms  of electrocyclic, cycloaddition and sigmatropic reactions.

CHEM-361 Lab:

Experiments involving aromatic substitution, oxidation/reduction reactions and pericyclic   reactions,   nitration   of   nitrobenzene   to   meta-dinitrobenzene, reduction of meta- dinitrobenzene to meta-nitroaniline, sulphonation of aniline, oxidation of benzaldehyde, oxidation of cyclohexanol to cyclohexanone. Preparation of  benzoic acid  and  benzyl  alcohol from  benzaldehyde using Cannizzaro’s reaction.